GRANDACTIVE RETINOID 2%
The latest generation retinoid HPR (Hydroxypinacolone Retinoate) is a new ester of retinoic acid. It binds directly to the retinoid receptors of skin cells and takes effect without causing side effects like other retinoids. HPR regulates the transfer of genetic information from DNA to RNA, stimulates the synthesis of collagen, moisturizes glycosaminoglycans, and filaggrin protein, which is responsible for cytoskeleton stability. It also inhibits the activity of matrix metalloproteinases – enzymes that destroy collagen, which are activated by UVB radiation and other pathological factors. HPR thin the upper stratum layer of the epidermis consisting of dead horny scales, which leads to the reduction of wrinkles. By normalizing keratinization processes, it prevents the clumping of horny scales, which can clog pores. It also helps to normalize the production of sebum, which eliminates inflammatory acne-like rashes. Additionally, it whitens the skin and prevents the accumulation of melanin in the layers of the dermis and epidermis.

RENOVAGE
A unique peptide complex to thicken skin and for skin turgor. It specifically improves the structure of the dermal matrix. Biological studies have found that the life of a cell culture under the influence of Renovage increased by 1/3, and cell aging slowed down by 3.5 months. The complex provides an anti-age and protective effect by stabilizing telomeres and maintaining cell DNA. Improves tissue quality by regulating the activity of isoprenoids, which bind proteins in cells and direct them to the synthesis of the extracellular matrix, to the synthesis of transmembrane carriers for improved intercellular contact.

SWEET ALMOND OIL contains a large number of vitamins – A, C, E, B, as well as phylloquinone – a type of vitamin K, effectively reducing the permeability of the capillary wall and reducing the manifestations of couperose. Antioxidant activity of the oil is manifested due to the high content of polyphenolic compounds in the oil – protocatechuic, p-hydroxybenzoic, vanillic acids. The peculiarity of almond oil is its duality: on the one hand, it is very nourishing and perfectly softens the skin, but on the other hand – it is very light and is instantly absorbed into the skin without leaving a greasy feeling.
Sweet almond oil is a rich source of fatty acids, primarily oleic and linoleic acids. Oleic acid is involved in regulating the concentration of cholesterol in cell membranes, affecting their rigidity, which helps to restore skin elasticity. In addition, oleic acid has a striking feature – in the area of the double bond it has a spatial curvature, due to which the length of the fatty acid chain decreases and the volume occupied by it increases. This feature determines the pronounced penetrating ability of oleic acid and its enhancer properties.
Linoleic acid is a binding component in the structure of the epidermis, regulating the development of keratinocytes. It has a strong anti-inflammatory effect, reduces skin reactivity, increases local immunity.

GRAPE SEED OIL is obtained by cold pressing, which allows it to retain all the important biologically active substances that determine its regenerative, antioxidant and cytoprotective properties. The oil is rich in micro and macro elements, essential fatty acids – linoleic (up to 70%), oleic, palmitic, vitamins A, B, C, E, natural chlorophyll, and flavonoids. Flavonoids contained in grape seed oil – resveratrol and proanthocyanidin have a very high degree of antioxidant activity and provide the most effective protection against free radicals. Proanthocyanidin is a very powerful natural antioxidant whose effect on free radicals is many times greater than of vitamins C and E.
Resveratrol has a similar biological function and structure to estradiol. It helps to normalize the estrogen balance and promote the natural collagen synthesis necessary for skin firmness and elasticity. Resveratrol stimulates superoxide dismutase which can neutralize free radicals and inhibit the skin’s lipid peroxidation reaction.
Grape seed oil is very light and delicate. It is also quickly absorbed without leaving a greasy film. That is why it is used in cosmetics as a care for all skin types, including oily skin, as the oil has bactericidal properties and helps to normalize sebum activity and narrow pores.

Apply to cleansed dry skin only at night. After 10-15 minutes apply the cream! It is recommended to gradually increase the dose depending on the sensitivity of the skin and the purpose of using the serum, the course is adjusted individually. During the first 10 days, we recommend using the serum every 3 days. From the 11th to the 20th day, use it every second day, and from the 21st day, we recommend using it every day. The full course of treatment is 60 days.